Synthesis of New Fluorine/Phosphorus Substituted 6-(2’-Amino Phenyl)-3-Thioxo-1,2,4-Triazin-5(2H, 4H)One and Their Related Alkylated Systems as Molluscicidal Agent as against the Snails Responsible for Bilharziasis Diseases
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Synthesis of 2-phenyl-5-sulpha/substituted-3- substituted phenyl azo indoles used as antifertility agent
–A novel series of 2-phenyl-5-sulpha/substituted-3-phenyl substituted azo indoles have been synthesized and tested as an antifertility activity in mature albino mice. The tested compounds showed significant antifertility activity. Keywords––Synthesis, Antifertility activity, Indore, Azo indoles, chemical analysis.
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چکیده ندارد.
Synthesis and evaluation of 2-substituted-6-phenyl-4,5-dihydropyridazin-3(2H)-ones as potent inodilators.
The present study describes the synthesis and pharmacological evaluation of 2-substituted-6-(4-acylaminophenyl)-4,5-dihydropyridazin-3(2H)-ones as potent inodilating agents. The synthesis of target compounds 2-4 and 7-11 was achieved by Friedel-Crafts acylation of appropriate anilide derivative with succinic anhydride or methylsuccinic anhydride and subsequent cyclization of intermediary keto a...
متن کاملSynthesis and in-vitro antifungal activity of 6-substituted-phenyl-2- {[(4'-substituted phenyl-5'-thioxo)-1,2,4-triazol-3-yl]-methyl}-2,3,4,5-tetrahydropyridazin-3-one derivatives.
The synthetic pathway for 6-substituted phenyl-2-[{(4'-substituted phenyl-5'-thioxo)-1,2,4-triazol-3-yl}-methyl]-2,3,4,5-tetrahydropyridazin-3-one compounds was achieved by a sequence of reactions starting from respective aryl hydrocarbons and is illustrated in Scheme 1. All the compounds were tested for their in vitro antifungal activity on five fungal species, namely Candida albicans, Trichop...
متن کاملA NEW SPECTROPHOTOMETRIC PROCEDURE FOR THE DETERMINATION OF NICKEL (11) USING 6-PHENYL-2,3-DIHYDRO-AS-TRIAZINE-3 –THIONE
A spectrophotometric procedure for the determination of Nickel (??) based on the complex formation with 6-phenyl-2, 3-dihydro-as-triazine-3-thione (PDTT) was developed. A yellow compound forms and is easily extractable by chloroform at pH>6. The mole ratio between Nickel (??) and PDTT is 1:4. The absorbance of the complex obeys Beer's law over the concentration range of 1-7 ug of Ni (??) pe...
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ژورنال
عنوان ژورنال: International Journal of Organic Chemistry
سال: 2014
ISSN: 2161-4687,2161-4695
DOI: 10.4236/ijoc.2014.42017